Life On Warfarin

My Warfarin Blog Contact Me
 

What Is Warfarin?

 

Warfarin (also known as Coumadin) is an anticoagulant that works by inhibiting Vitamin K-dependent coagulation factors.

  • Theraputic doses of warfarin decrease the effects of Vitamin K-dependant clotting factor by approximately 30% to 50%.  
  • An anticoagulation effect generally occurs within 24 hours after the drug administration, though peak anticoagulant effect may be delayed 72 to 96 hours.  
  • The  action of a single dose of warfarin lasts 2 to 5 days, & the effects of warfarin may become more pronounced as effects of daily doses overlap.  
  • The dosage & administration of warfarin is individualized for each warfarin patient in accordance to the particular patient's PT/INR response to the drug.  

The elimination of warfarin is almost entirely by metabolism. Warfarin is eventually metabolized to reduced metabolities (warfarin alcohols), & excreted into the urine, & sometimes, the bile.

The objective of anticoagulation therapy is to decrease the clotting ability of blood so that blood clot is prevented, while avoiding spontaneous bleeding.

  • Numerous factors, alone or in combination including changes in diet, medications, botanicals etc may affect patient's response to warfarin. Therefore, regular PT/INR monitoring is advisable.  
  • An INR of greater than 4.0 appears to provide no additional theraputic benefit in most patients & is associated with higher risk of bleeding.  

 

Other Observations Include:

  • Elderly patients who are 60 years or older seem to exhibit greater than expected PT/INR response to the anticoagulant effects of warfarin. Hence, a lower dose of warfarin is usually required to produce similar therapeutic level of anticoagulation as patient age increases.
  • Asian patients may require lower initiation & maintenance doses of warfarin.

 

 *Above information is extracted from Bristol-Myers Squibb website. Special thanks to SDS, for sharing this information link.

The Sinatra Solution: For Heart Patients With Low Energy Level 

Sinatra Solution - For Patients With Heart Disease

$17.13 from Amazon 

Dr. Sinatra Recognizes The Value of Nutritional Supplements Which Allow Body To Heal Itself.

Learn How He Incorporates Use of Proven Supplements
(supported by scientific studies) In Addition To Traditional Treatments, Diet & Exercise.

A Must Read For Cardiac Patients. 

 

Coumadin (Warfarin) Help Book

Coumadin (Warfarin) Help Book

$10.17 from Amazon 

Coumadin® can be challenging to manage.

The author Diana Schneider explains how Coumadin® works, & how food and medications can alter its effects. She also provides information on how to enjoy a normal, healthy diet while using the drug, manage unusual situations, travel with Coumadin®, and much more.


A Handy Manual & Guide For Coumadin / Warfarin Patients. 

 

Omron HEM-790IT Automatic Blood Pressure Monitor with Advanced Omron Health Management Software

Omron HEM-790IT Automatic Blood Pressure Monitor

$73.27 from Amazon

Extremely accurate & reliable, this IntelliSense Monitor Allows Users To Monitor/ Detect Irregular Heartbeats & Hypertension effortlessly at home.

Great for Better Management of Hypertension & Heart Problems, as Users Can Keep Track of Own Range of Readings & Provide Valuable Information to Healthcare Professionals.

Bell Uses This Useful Device & Recommends It to Whoever May Need It.